Targeting Gene Fusion Events in Bladder Carcinoma
نویسندگان
چکیده
منابع مشابه
The vascular-targeting fusion toxin VEGF121/rGel inhibits the growth of orthotopic human bladder carcinoma tumors.
Vascular endothelial growth factor (VEGF) and its receptors (FLT-1 and KDR) are overexpressed by human bladder cancer cells and tumor endothelial cells, respectively. Strategies that target VEGF receptors hold promise as antiangiogenic therapeutic approaches to bladder cancer. A fusion protein of VEGF121 and the plant toxin gelonin (rGel) was constructed, expressed in bacteria, and purified to ...
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ژورنال
عنوان ژورنال: Journal of Molecular and Genetic Medicine
سال: 2018
ISSN: 1747-0862
DOI: 10.4172/1747-0862.1000361